Description: http://staticapp.icpsc.com/icp/loadimage.php/mogile/815859/4451f83903a49598dc178e1060dc9057/image/jpeg

 

Now Open: First Clinical Trial to Evaluate Metformin for the Treatment of Endometrial Hyperplasia

 

Description: http://staticapp.icpsc.com/icp/loadimage.php/mogile/815859/913c26568127e8b875917e0f95439572/image/jpegDrs. Ko and Bae-Jump, along with Dr. John Byron, are leading a multi-institutional pilot clinical trial to assess the efficacy of metformin in the treatment of women with simple and complex endometrial hyperplasia without atypia at UNC Chapel Hill and Southern Pines Women’s Health Center.

 

Potential biomarkers of treatment response will also be explored, including metabolic factors and molecular markers of downstream targets of the metformin/mTOR signaling pathway. Patients will be enrolled through the general gynecology and gynecologic oncology clinics.

 

For more information or to refer a patient, call 919-843-2343.

 

Recent Study Looks at Minimally-Invasive Surgical Approaches

 

Description: http://staticapp.icpsc.com/icp/loadimage.php/mogile/815859/cbc9726af86f4b5bc04ae9a5d8e998a0/image/jpegA new technique for minimally-invasive sentinel lymph node sampling may reduce the risk of long-term complications for patients with cervical and endometrial cancer, according to a feasibility study conducted at the University of North Carolina.

 

“While more research needs to be conducted in a broader patient population, we know that the benefits of minimally-invasive surgical approaches to these cancers are significant for patients. Our results suggest that this technique can increase confidence that sentinel lymph node biopsy can be conducted in a thorough manner with actionable results for the patient’s cancer treatment plan with a minimally-invasive approach that speeds healing time and can be less painful for the surgical patient,” said principal investigator John Boggess, MD.  The investigators are undertaking the required regulatory steps to allow additional women to be offered enrollment into this study. Read more.

 

 

New Referral and Outreach Options

 

Description: http://staticapp.icpsc.com/icp/loadimage.php/mogile/815859/3f2d74d800e9f19cdf361f27844850d5/image/jpegDr. Kenneth Kim recently joined the Division of Gynecologic Oncology at the University of North Carolina. He comes to UNC from the University of Alabama where he completed his fellowship training in Gynecologic Oncology. He earned his medical degree and completed his residency in Obstetrics and Gynecology at The Ohio State University.

 

The addition of Dr. Kim will allow for the expansion of referral and patient care services at UNC and at Rex Hospital in Raleigh, NC. He will join Drs. John Soper, John Boggess, and Linda Van Le and nurse practitioner Pat Butterton in providing coverage Monday - Friday for gynecologic oncology consultative services, both inpatient and outpatient, and operative consultation and procedures. 

 

Consultative and operative services are also provided at Wesley Long Hospital in Greensboro, NC.  Wesley Long Hospital is part of the Moses Cone Hospital System. Drs. Daniel Clarke-Pearson, Wendy Brewster and Paola Gehrig travel to Greensboro approximately two days a week, allowing women to receive subspecialty care in their community hospital.  Nancy Wilkinson, RN, coordinates and manages the practice, and there are plans to add an additional nurse practitioner in the near future.

 

Description: http://staticapp.icpsc.com/icp/loadimage.php/mogile/815859/f129724cc6a5c1d4c98546bb4c913638/image/jpegGroesbeck Parham, MD and Charla Chibwesha, MD, MSc (shown here with Susan Banda, NP) lead an extensive outreach and screening program for cervical cancer in Zambia.

 

Read more.

 

UNC Fertility Preservation Program

 

The UNC Fertility Preservation Program is a multi-disciplinary clinic of reproductive endocrinologists, oncologists, and psychologists. The program's goal is to provide information, counseling, support, and state-of-the-art treatment options for patients with cancer and other illnesses requiring treatment that seriously threatens future fertility. Services are offered at two locations:  UNC Women’s Hospital in Chapel Hill and the UNC Specialty Women’s Center at Rex Hospital in Raleigh.

 

“Fertility preservation is medically complex and emotionally challenging,” notes Jennifer Mersereau, MD, Director of the Fertility Preservation Program.  “We’re dedicated to offering the most complete range of options for fertility preservation in a compassionate, personal environment.” Read more.

 

The Elderly and Cancer

 

Description: http://staticapp.icpsc.com/icp/loadimage.php/mogile/815859/803532a66f255852fb4509b618bd7b2a/image/jpegWith the creation of the UNC Elderly Working Group, a critical mass of investigators have come together to study the impact of cancer and its treatment in the elderly population. Drs. Van Le and Muss have launched LCCC1015 “Use of Palliative Performance and Symptom Distress Scales in Older Patients with Advanced Ovarian Cancer." The goal of this study is to assess the impact of cancer surgery and chemotherapy on cognitive, emotional, and physical function in older patients. Another study planned to open soon will look at the impact of chemotherapy for recurrent endometrial cancer, to determine the impact on quality of life in older patients.

 

Nationally, the Gynecologic Oncology Group has recognized the special needs and characteristics of the elderly group and has launched the clinical trial GOG 273 “Chemotherapy Toxicity in Elderly Women with Ovarian, Primary Peritoneal or Fallopian Tube Cancer” which will evaluate the impact of treatment on elderly patients for a broader group of tumors. This trial is also available for gynecologic cancer patients at UNC.

 

Other Specialty Services

The Center for Women’s Health Research at UNC (CWHR) has recently added two new clinical trials to the list of 15 women’s health focused projects administered by the center. Read more.

 

Cancer Survivorship and Exercise - Contact Paola Gehrig, MD, at 919-966-1994 for more information.

 

 

Contact Information

 

To make a referral to the UNC program, call coordinator Katrina Moore at 919-966-7822.

 

To make a referral to the program at Rex, call coordinator Mary Culbreth, RN, at 919-784-6875.

 

To make a referral to the program in Greensboro, call coordinator Nancy Wilkinson, RN, at 336-832-1895.

 

For more information about clinical trials, call Elizabeth Hill at 919-843-1656.

 

UNC Lineberger    N.C. Cancer Hospital    Clinical Trials     Clinical Programs    Comprehensive Cancer Support

 

For questions about all clinical trials at UNC (including those at UNC that are also offered at other sites), contact the UNC Lineberger protocol office at 919-966-4432 or (toll-free) 1-877-668-0683.

 

To make an appointment at the N.C. Cancer Hospital for one of your patients, visit our web page for referring physicians. You may also contact the Carolina Consultation Center at 1-800-862-6264.