Last Updated: 12/15/2008

J.S. Marron, PhD Amos Hawley Distinguished Professor Cancer Genetics, Breast Cancer

Research Interests
Statistics and genetics, visualization of data, High Dimension Low Sample Size data analysis. Currently working on the genetics underlying breast, lung and pancreatic cancers. Also collaborating on an image analysis approach to microscopic images for diagnosis of melanoma.

Recent Accomplishments and Honors
S. N. Roy Memorial Lecture, University of Calcutta, 2004.

Institute of Mathematical Statistics Medallion Lecturer, 2003.

Special Invited Article, Journal of Computational and Graphical Statistics, 2002.

Number 15 on ISI List of Most Highly Cited Mathematicians (over all mathematical sciences), 1991-2001.

Training
Ph. D., Mathematics, University of California, Los Angeles, 1982 (thesis advisor: Charles J. Stone)

M. S., Mathematics, University of California, Los Angeles, 1980

B. S., Mathematics, University of California, Davis, 1977

A. A., Orange Coast College, 1974

Publications
Selected recent cancer related papers, from over 120 total published in refereed journals:

Statistical Significance of Clustering for High Dimension Low Sample Size Data, Liu, Y., Hayes, D. N., Nobel, A. and Marron, J. S. (2008) Journal of the American Statistical Association., 103, 1281-1293.

Support Vector Machine for Data on Manifolds: An Application to Image Analysis, Sen, S., Foskey, M., Marron, J. S. and Styner, M. (2008) IEEE International Symposium on Biomedical Imaging, Paper Code: SA-P1b.3

A scale-based approach to finding effective dimensionality in manifold learning, Wang, X. and Marron, J. S. (2008) Electronic Journal of Statistics, 2, 127-148.

The high-dimension, low-sample-size geometric representation holds under mild conditions, Ahn, J., Marron, J. S., Muller, K. M. and Chi, Y.-Y. (2007) Biometrika, 94, 760-766.

Distance Weighted Discrimination, Marron, J. S., Todd, M. J. and Ahn, J. (2007) Journal of the American Statistical Association, 102, 1267-1271.

Analysis of nonlinear modes of variation for functional data, Izem, R. and Marron, J. S. (2007) Electronic Journal of Statistics, 1, 641-676.

Object oriented data analysis: sets of trees, Wang, H. and Marron, J. S. (2007) Annals of Statistics, 35, 1849-1873.

Singular Value Decomposition and Its Visualization, Zhang, L. Marron, J. S., Shen, H. and Zhu, Z. (2007), Journal of Computational and Graphical Statistics, 16, 833-854.

SiZer for time series: a new approach to the analysis of trends, Rondonotti, V., Marron, J. S. and Park, C. (2007) Electronic Journal of Statistics, 1, 268-289 (http://dx.doi.org/10.1214/07-EJS006).

A 10-gene classifier for distinguishing head and neck squamous cell carcinoma and lung squamous cell carcinoma, Vachani, A., Nebozhyn, N., Singhal, S., Alila, L., Wakeam, E., Muschel, R., Powell, C. A., Gaffney, P., Singh, B., Brose, M. S., Litzky, L. A., Kucharczuk, J., Kaiser, L. R., Marron, J. S., Showe, M. K., Albelda, S. M., Showe, L. C. (2007) Clinical Cancer Research, 13, 2905-15.

Discrimination Analysis using Multi-object Statistics of Shape and Pose, Gorczowski, K., Styner, M., Jeong, J.-Y., Marron, J. S., Piven, J., Hazlett, H. C., Pizer, S. M. and Gerig, G. (2007) Proc SPIE, vol. 6512, no. , pp. 1-8.

Statistical Shape Analysis of Multi-Object Complexes, Gorczowski, K., Styner, M., Jeong, J.-Y., Marron, J. S., Piven, J., Hazlett, H. C., Pizer, S. M. and Gerig, G. (2007) IEEE - Computer Vision and Pattern Recognition 2007, pp. 1-8, June 2007.

The high-dimension, low-sample-size geometric representation holds under mild conditions, Ahn, J., Marron, J. S., Muller, K. M. and Chi, Y. - Y. (2007) Biometrika, 94, 760-766.

The molecular portraits of breast tumors are conserved across microarray platforms, Hu, Z., Fan, C., Oh, D. S., Marron, J. S. He, X., Qaqish, B. F., Livasy, C., Carey, L. A., Reynolds, E., Dressler, L., Nobel, A., Parker, J., Ewend, M. G., Sawyer, L. R., Wu, J., Liu, Y., Nanda, R., Tretiakova, M., Orrico, A. R., Dreher, D., Palazzo, J. P., Perreard, L., Nelson, E., Mone, M., Hansen, H., Mullins, M., Quackenbush, J. F., Ellis, M. J., Olopade, O. I., Bernard, P. S., Perou, C. M. (2006) BMC Genomics, 7, 96.

Discrimination of Mechanical Response to ARFI Excitation in a Raised Atherosclerotic Plaque, Levy, J. H., Behler, R., Haider, M. A., Marron, J. S. and Gallippi, C. M. (2006) MICCAI Workshop on Computer Vision for Intravascular and Intracardiac Imaging (G. Unal, I. Kakadiaris, G. Slabaugh, and A. Tannebaum, eds.), 58-65.

Geometric representation of high dimension, low sample size data (2005) Hall, P. Marron, J. S. and Neeman, A., Journal of the Royal Statistical Society, Series B, 67, 427-444.

Adjustment of systematic microarray data biases (2004) Benito, M. Parker, J. Du, Q., Wu, X. Xiang, D., Perou, C. M. and Marron, J. S., Bioinformatics, 20, 105-114.

SiZer for length biased, censored density and hazard estimation (2004) de Ua lvarez, J. and Marron, J. S., Journal of Statistical Planning and Inference, 121, 149-161.

The Functional Data View of Longitudinal Data (2004) Zhao, X., Marron, J. S. and Wells, M. T., Statistica Sinica, 14, 789-808.

Statistical Significance of Features in Digital Images (2004) Godtliebsen, F., Marron, J. S. and Chaudhuri, P., Image and Vision Computing, 22, 1093-1104.

Repeated observation of breast tumor subtypes in independent gene expression data sets, (2003) Srlie, T., Tibshirani, R., Parker, J., Hastie, T., Marron, J. S., Nobel, A., Deng, S., Johnsen, H., Pesich, R., Geisler, S., Demeter, J., Perou, C. M., Lnning, E. E., Brown, P. O., Brresen-Dale, A.-L. and Botstein, D. Proceedings of the National Academy of the Sciences of the U S A., 100, 8418-23. Epub 2003 Jun 26

Mixed-model functional ANOVA for studying human tactile perception Spitzner, D. J., Marron, J. S. and Essick, G. K. (2003) Journal of the American Statistical Association, 98, 263-272.

E-mail: marron@email.unc.edu
Telephone: 919-962-2188
FAX: 919-962-1279
Address: 3049 Smith Chapel Hill, NC 27599-3260
URL: http://www.stat.unc.edu/faculty/marron.html

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